Biotechnology and Interaction Design
AGU is a three letters word that stands either for my short-name and for the ARNm triplet that codes Serine, an amino acid presented in all of us.
As you may remember from school, biology is built from tiny parts that just interact between themselves in a mechanical way that leads to bigger, greater and complex things.
The little strands called DNA, replicated almost one hundred trillion times in your body, and which could surround the entire earth (each strand), have written in them each detail of what you see every morning in the mirror.
At some point in the cell's life, those strands start to get transcribed into RNA chains, a middle-man molecule in the process of polypeptides synthesis.
Once a polypeptide strand is completed by hundreds and even thousand amino acids, it starts to fold in unpredictable forms until it shapes the final structure, revealing a protein, the engine of life.
This plethora of magical steps occurs in a deterministic way, several times per minute in every single organism.
Do you recognize this?:
gagtgcttgg gttgtggtga aacattggaa gagagaatgt gaagcagcca ttcttttcct gctccacagg aagccgagct gtctcagaca ctggcatggt gttgggggag ggggttcctt ctctgcaggc ccaggtgacc cagggttgga agtgtctcat gctggatccc cacttttcct cttgcagcag ccagactgcc ...
This is an extract from the DNA which codes the p53 protein, one of the most globally studied molecules involved in cancer development, well known as the star of cancer suppression proteins.
And what about this other piece of code?:
8B542408 83FA0077 06B80000 0000C383 FA027706 B8010000 00C353BB 01000000 B9010000 008D0419 83FA0376 078BD98B C84AEBF1 5BC3
This strange code is all you need to program the fibonacci serial in the low-level machine language. Executable by almost every gadget around you. See what both codes have in common?
Scientists and tech people have worked really hard during last decades building levels of abstraction. Look inside and you will find a large amount of conceptual layers from ones and zeros to the graphical user interface, each one simpler than the previous. All drives in the direction that nobody needs to think on hexadecimal to send a plain email.
Have you ever think about a cell as a machine?. They really behave like it whether they are yeast or pluripotent cells in your bone marrow. In fact, as Drew Endy define them, they act as computational systems. They receive inputs, and behave accordingly as outputs. Cells have measurements tools, priorities to satisfy and self awareness of different kinds.
DNA is a reference of functions for a certain being, as software is for an application.
The only difference between software and life source code is the abstraction layers created that enables us to understand, write and debug what we do in a computer. Fortunately, that complex frontier between life in nature and what can be done in a lab by humans is breaking down throughout international cooperation in biology and health research.
Knowledge repositories about enzyme interactions in pathways, expression rules of genes and protein transcriptions are spreading all over the web in different public databases.
Although work with bulk data in these databases is still a hard task, little pieces of proteins interactions are been described and identified as functions in projects like the "Registry of Standard Biology Parts", initiated by previously cited Drew Endy. Basic biological functions are explained in its website as simple parts that get combined making devices and systems. The result is a hierarchical scheme of complex behaviors.
Craig Venter used to say "Electronic industry is based upon 12 fundamental components. Up to now, 20 million genes had been identified."
The faculty for using these genes as pieces of code in engineered organisms have an unprecedented potential in creating new things.
OK, but what does all this have in common with interaction design?. As defined in wikipedia, "Interaction Design is the discipline of defining the behavior of products and systems that a user can interact with."
As you can find in some related lectures, biology must be understood as a technology. A technology for creating complex things with complex implications.
As designers, we are used to deal with problem solving tasks, requirements, and constraints. Biotechnology industry is developing extremely fast, enabling a myriad of applications for new products and services based on biology.
Many authors describe the necessity of compartmentalize competences in biotechnology. Specialization brings better quality in every decision step. From laboratory operators to the function of a biological engineer as a technical architect, someone has to deal with the human side of the final product.
As interaction designers we can apply all the inherited knowledge in our discipline to new horizons like biotech. It's just a new framework with new variables.
Juan Leal dijo
Thanks for sharing this wonderful post. You talked about so many details in your last speech that it was necessary to have it written :)
18 Agosto 2008 | 09:42 AM